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25-Dec-2015 02:25

We assessed the performance of six existing ultrasound reference charts to determine gestational age in 1268 singleton IVF pregnancies, where “true” gestational age could be precisely calculated from date of fertilisation.All charts generated dates significantly different to IVF dates ( all comparisons). This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Accurate determination of gestational age underpins good obstetric care.It is therefore a good time in pregnancy to determine gestational age by ultrasound where the crown-rump length (CRL) is measured and compared to published reference charts.In contrast, dates calculated from the first day of the last menstrual period (menstrual age) may have inaccuracies arising from imprecise recollection of dates, variation in the timing of ovulation, or time to conception.

In the first trimester, there is a very little biologic variation in fetal size compared with later trimesters.A number of CRL reference charts have been proposed and different versions are in common use (Table 1).